This purified mouse anti-Complex I monoclonal antibody recognizes Complex I NDUFA9. Complex I, or NADH ubiquinone oxidoreductase, is a large protein complex of 950,000 Da molecular weight made up by 45 to 46 different subunits. Complex I is sensitive to a wide range of inhibitors, many of which are pesticides or other common environmental toxins, such as rotenone. Western Blotting is the validated application for use with Mouse anti-Complex I NDUFA9 Monoclonal Antibody.

Antibody Specifications:

• Applications: Validated application for Mouse anti-Complex I Monoclonal Antibody is Western Blotting.
• Host Species and Isotype: The host species and isotype of the anti-Complex I Monoclonal antibody is mouse IgG1-κ.
• Clone ID of Monoclonal Antibody (mAb): The monoclonal antibody clone is 20C11B11B11.
• Reactivity: Reacts with human, bovine, mouse, and rat Complex I.
• Product Size: mouse anti-Complex I Monoclonal Antibody is available in a 100 µg size.

Complex I, or NADH ubiquinone oxidoreductase, is a large protein complex of 950,000 Da molecular weight made up by 45 to 46 different subunits. A total of seven of the subunits of the complex are encoded by mitochondrial DNA, while the remainder subunits are nuclear encoded, which are translated in the cytosol and trans-located into the organelle for assembly at the inner membrane. The enzyme complex catalyses electron entry from NADH via a flavin (FMN) and several non-heme iron centers. Complex I is sensitive to a wide range of inhibitors, many of which are pesticides or other common environmental toxins, such as rotenone.