Mitogen-Activated Protein Kinase Kinases 3 and 6 (MEK3⁄6 or MKK3⁄6) are 42 kDa members of a tyrosine⁄threonine protein kinase family that activate p38, which is part of the inflammation⁄ stress signaling pathway. Phosphorylation of MEK3 and 6 by MEKK1 on serine 189 and threonine 193 (serine 207 and threonine 211 for MEK6) in the catalytic domain activates the proteins and enables them to phosphorylate p38.
MEK3⁄6 [pSpT189⁄193]⁄[pSpT207⁄211], Rabbit Polyclonal Antibody-Unconj is reactive to human MEK4 and is validated in Western Blot. Mek 3 is also known as MEK3; MKK3; MAPKK3; PRKMK3; MAP2K3, Dual specificity mitogen-activated protein kinase kinase 3,MAP kinase kinase 3, MAPK⁄ERK kinase 3, MAP2K3, MEK3, MKK3, PRKMK3 with Hu Gene ID: 5606. MEK 6 is also known as MAP2K6, mitogen-activated protein kinase kinase 6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3, protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6), Hu Gene ID: 5608.
Catalog number 44470G is the same antibody as former catalog number 44470. 44470G contains 50% glycerol, which improves the stability and longevity of this antibody.