Retinoid X receptor-α (RXR-α; NR2B1) is a member of the orphan nuclear receptor family. 9-cis retinoic acid can bind to RXR. RXR-α is expressed in liver, muscle, lung, kidney, intestine, heart and spleen. RXR-α plays an important role in a variety of processes including embryonic patterning and organogenesis, cell proliferation and differentiation. RXRs commonly function as heterodimers with other members of the nuclear receptor superfamily.
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human RXR-α (2-133 aa).
This antibody specifically recognizes human RXRα and cross reacts with mouse and rat RXRα. This antibody does not recognize human RXRβ and γ.
Hu, Ms, Rt
Western Blot, ELISA, Electrophorectic Mobility Shift Assay, Immunoprecipitation, Chromatin Immunoprecipitation, Immunohistochemistry (WB, E, EMSA, IP, ChIP, IHC)