This purified mouse anti-TRA-1-60 monoclonal antibody is specific to the TRA-1-60 antigen. The TRA-1-60 antigen is expressed by human embryonal carcinoma (EC) cells and is associated with a polydisperse glycoprotein with a molecular weight in excess of 200,000 Da. Anti-TRA-1-60 monoclonal antibody is used in western blotting, immunofluorescence, and immunoprecipitation (native) applications.

Antibody Specifications:

• Applications: Validated applications for anti-TRA-1-60 monoclonal antibody are western blotting, immunofluorescence, and immunoprecipitation (native).
• Host Species and Isotype: The host species and isotype of the antibody is mouse IgM.
• Clone ID of Monoclonal Antibody (mAb): The monoclonal antibody clone is cl.A.
• Reactivity: Reacts with human TRA-1-60 antigen.
• Product Size: Mouse anti-TRA-1-60 monoclonal antibody is available in a 100 µg size.

The TRA-1-60 antigen is expressed by human embryonal carcinoma (EC) cells and is associated with a polydisperse glycoprotein with a molecular weight in excess of 200,000 Da. TRA-1-60 recognizes an antigen of similar size as detected by TRA-1-81, GCTM2, K4, and K21, and all these antibodies detect similar but distinct patterns of expression on panels of tumor-derived cell lines. TRA-1-60 and TRA-1-81 epitopes are associated with distinct molecular species. TRA-1-60, TRA-1-81, GCTM2, and K21 antibodies all recognize distinct epitopes formed by modifications of a common keratan sulfate core molecule that is characteristically expressed by human EC cells. TRA-1-60, clone cl.A, likely recognizes the carbohydrate part of the molecule, as TRA-1-60 activity is destroyed by neuraminidase.