The BioPrime® DNA Labeling System is ideal for generating biotinylated DNA probes by random priming for use in non-radioactive Southern or northern blots, plaque lifts, colony hybridizations, and in situ hybridizations (1,2). The BioPrime® DNA Labeling System:

• Requires less template DNA than nick translation

• Amplifies template to provide an increased amount of biotinylated probe

• Labels 50 to 500 ng of template DNA in one reaction