Dynabeads® Human T-Activator are coupled with anti-CD3, anti-CD28, and anti-CD137 antibodies. CD137 (4-1BB) is a member of the tumor necrosis factor family. Agonistic anti-CD137 antibody acts as an activating costimulatory molecule especially important for effector/memory T cells and promotes the survival and proliferation of T lymphocytes.
- Efficient expansion and increased survival rate of Ag-specific T cells
- No need to find or prepare donor-matched MNC or antigen
- T cells expanded with Dynabeads® maintain Ag-specific responses
