Dynabeads® CD19 pan B are magnetic beads that provide a robust and versatile tool to isolate or deplete human CD19+
B cells directly from any sample, including whole blood, bone marrow, buffy coat, mononuclear cells (MNC), and tissue digests.
• Rapid isolation of CD19+
B cells from any sample – no columns required
• Positive isolation for molecular downstream assays or efficient depletion of CD19+
B cellsExcellent Yield, Purity, and Viability of Recovered Cells
Dynabeads® CD19 Pan B are uniform, superparamagnetic beads (4.5 µm diameter) that enable easy isolation of human CD19+
B cells directly from any sample. Dynabeads® CD19 pan B beads are coated with a primary monoclonal antibody specific for the CD19 membrane antigen mainly expressed on human B cells. Dynabeads® CD19 pan B bind to CD19+
cells during a short incubation period in a tube, after which the bead-bound cells are separated from unbound cells using a magnet
. This fast and gentle isolation method does not require the use of columns, and helps ensure high purity, recovery and viability of the isolated CD19+
cells.Ideal for Both Depletion and Positive Isolation for Downstream Molecular Assays
Because of the powerful magnets used for separation, Dynabeads® CD19 pan B can be used in viscous samples such as whole blood and bone marrow and thus give efficient depletion of CD19+
cells in about 30 minutes. Dynabeads® CD19 pan B will also afford excellent recovery of high-purity, viable cells for use in downstream molecular studies; for example, those in which cells are to be lysed while still attached to beads, and nucleic acids or proteins further purified. Note that intact cells will not be released from these beads, so if you want to isolate CD19+
cells for cell-based applications, or you need to check your samples with flow cytometry, you should use DETACHaBEAD® CD19
(for bead- and antibody-free cells) or Dynabeads® Untouched™ Human B Cells
to obtain untouched human B cells.
Select what is right for you from our range of Human B Cell Isolation Products
For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.