This monoclonal antibody reacts with an antigen present in fetal and neonatal melanocytes and junctional nevi. Intradermal nevi and normal adult melanocytes are negative. Positive tissue: Melanoma.

Clone/PAD: HMB45

Immunogen: Pigmented melanoma metastes to lymph node

Specificity: Reacts with an antigen present in fetal and neonatal melanocyte and junctional nevi. Intradermal nevi and normal adult melanocytes are negative.

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Not required, Enzyme Digestion: Not required

Expected Staining Pattern: Cytoplasmic