This polyclonal antibody reacts with human synaptophysin. Synaptophysin (38 kDa) is a membrane component of the synaptic vessicle present in neurons and neuroendocrine cells. May be useful in identifying tumor cells of neuroendocrine origin. Positive tissue: Pancreas/neuroendocrine tumors.

Clone/PAD: Z66

Immunogen: C-terminus of human synaptophysin

Specificity: This polyclonal antibody reacts with human synaptophysin.

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Not required, Enzyme Digestion: Not Required. Enzyme Digestion (Digest-All™ 2/Trypsin) may enhance staining.

Expected Staining Pattern: Predominantly cytoplasmic